Recall : Rejection of kidney, + elevated LFT: CMV
A renal transplant patient presents with rising creatinine and elevated liver function tests. He also has low-grade fever and malaise. CMV PCR comes back positive. What is the most likely cause of his current condition?
A) Acute rejection
B) Drug-induced hepatotoxicity
C) CMV infection
D) Hepatitis C reactivation
Correct answer: C) CMV infection
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Note :
Conclusion: CMV infection is important predisposing factor for acute allograft rejection after kidney transplantation. The results of this study suggests that the control of CMV infection could decrease episodes of acute kidney rejection.